Inter secured a 3-1 victory over Empoli and is now in second place, trailing Napoli by 3 points, but the Nerazzurri have a game in hand.
The goals for Inter were scored by Marcus Thuram, Lautaro Martinez, and Denzel Dumfries.
Mkhitaryan recovered from injury and entered the match in the 69th minute, replacing Zielinski. The Armenian midfielder recorded one key pass.
On January 22, Inter will play in the Champions League against Sparta Prague.